Updated publications from the Chen Lab at the Broad Institute.


Asano, S.M., Gao. R., Wassie. A.T., Tillberg, P.W., Chen, F., Boyden, E.S. Expansion Microscopy: Protocols for Imaging Proteins and RNA in Cells and Tissues. Current Protocols in Cell Biology. [Publisher link]



Zhao, Y., Bucur, O., Irshad, H., Chen, F., Weins, A., Stancu, A.L., Oh, E-Y., DiStasio, M., Torous, V., Glass, B., Stillman, I.E., Schnitt, S.J., Beck, A.H., Boyden, E.S. Nanoscale Imaging of Clinical Specimens Using Pathology-Optimized Expansion Microscopy. Nature Biotechnology. [Publisher link] [PDF]

Chang, J.B., Chen, F., Yoon, Y.G., Jung, E. E., Babcock H., Kang J.S., Asano S., Suk H.J., Pak N., Tillberg P.W., Wassie A., Cai D., Boyden E.S. Iterative expansion microscopy. Nature Methods. [Publisher link] [PDF]


Chen, F.*, Wassie, A.T.*, Cote, A.J., Sinha, A., Alon, S., Asano, S., Daugharthy, E.R., Chang, J.-B., Marblestone, A., Church, G.M., Raj, A., Boyden, E.S. Nanoscale Imaging of RNA with Expansion Microscopy. Nature Methods. (*equal contribution) [Publisher link] [PDF]

Tillberg, P.W.*, Chen, F.*, Piatkevich, K.D., Zhao, Y., Yu, C.-C., English, B.P., Gao, L., Martorell, A., Suk, H.-J., Yoshida, F., DeGennaro, E.M., Roossien, D.H., Gong, G., Seneviratne, U., Tannenbaum, S.R., Desimone, R., Cai, D., Boyden, E.S. (2016) Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies. Nature Biotechnology. (*equal contribution) [Publisher link] [PDF]

Zhang. Y.S., Chang J.B., Alvarez M.M., Trujillo-de Santiago G., Aleman J., Batzaya B., Kirshnadoss V., Ramanujam A.A., Kazemzadeh-Narbat M., Chen F., Tillberg P.W., Dokmeci M.R., Boyden E.S., Khademhosseini A. Hybrid Microscopy: Enabling Inexpensive High-Performance Imaging through Combined Physical and Optical Magnifications. Scientific Reports. [Publisher link] [PDF]


Chen, F.*, Tillberg, P.W.*, Boyden, E.S. Expansion Microscopy. Science. 347(6221):543-548. (*equal contribution) [Publisher link] [PDF]


Schmidt, D., Tillberg, P.W.*, Chen, F.*, Boyden, E.S. A fully genetically encoded protein architecture for optical control of peptide ligand concentration. Nature Communications. (*equal contribution)  [Publisher link] [PDF]